The Librarian
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Comparative effectiveness of epsilon-aminocaproic acid and tranexamic acid on postoperative bleeding following cardiac surgery during a national medication shortage.
Blaine KP, et al. J Clin Anesth. 2016.Abstract
STUDY OBJECTIVE: The aim of this study was to compare the effectiveness of epsilon-aminocaproic acid (εACA) and tranexamic acid (TXA) in contemporary clinical practice during a national medication shortage.
DESIGN: A retrospective cohort study.
SETTING: The study was performed in all consecutive cardiac surgery patients (n=128) admitted to the cardiac-surgical intensive care unit after surgery at a single academic center immediately before and during a national medication shortage.
MEASUREMENTS: Demographic, clinical, and outcomes data were compared by descriptive statistics using χ(2) and t test. Surgical drainage and transfusions were compared by multivariate linear regression for patients receiving εACA before the shortage and TXA during the shortage.
MAIN RESULTS: In multivariate analysis, no statistical difference was found for surgical drain output (OR 1.10, CI 0.97-1.26, P=.460) or red blood cell transfusion requirement (OR 1.79, CI 0.79-2.73, P=.176). Patients receiving εACA were more likely to receive rescue hemostatic medications (OR 1.62, CI 1.02-2.55, P=.041).
CONCLUSIONS: Substitution of εACA with TXA during a national medication shortage produced equivalent postoperative bleeding and red cell transfusions, although patients receiving εACA were more likely to require supplemental hemostatic agents.
Published by Elsevier Inc. -
Nairobi, Kenya - Man on a camel reads JW literature
Soon he will read about the Ethiopian eunuch reading while on a camel :-)
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They traveled from Spain to Colombia to preach where the need is greatest.will be there for the next 3 months and are sure to enjoy the experience of giving Jehovah the best of them!
Viajaron de España a Colombia para predicar donde la necesidad es mayor. Estaran allí durante los próximos 3 meses y están seguros de que disfrutaran la experiencia de dar a Jehová lo mejor de ellos !
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Jehovah’s Witnesses Public Talk Watchtower Study Meeting 11 December 2016
Please leave a comment below about something you enjoyed in this meeting.
Agape!
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Armed groups continue to forcibly take Kingdom Halls. Despite the challenges, the Witnesses persist in meeting together for worship with fellow believers.
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Special Assembly in Nairobi, Kenya
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Special Assembly in Nairobi, Kenya
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